MLKL

mixed lineage kinase domain-like

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

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Products

Antibodies (38)

Proteins (6)

ELISA Kits (4)

Type

Primary (38)

Recombinant (6)

Sandwich (4)

Target

MLKL (48)

Reactivity

Human (33)

Mouse (17)

Rat (7)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Pig (3)

Application

IHC (20)

IHC-P (7)

WB (22)

ELISA (15)

IF (2)

Peptide-ELISA (1)

Host

rabbit (29)

mouse (9)

Product Group

IHCPlus (2)

Isotype

IgG (24)

IgG1 (3)

IgG2a,k (1)

Clonality

monoclonal mc (8)

polyclonal pc (30)

Clone

3B2 (1)

8H7 (1)

Format

96-Well Strip Plate (4)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (27)

Epitope

aa443-472 (7)

aa1-471 (4)

aa107-156 (4)

40-120 aa, N-terminal (1)

aa110-135 (1)

pS358 (1)

Publications

No (46)

Yes (2)

Sample Type

Cell Lysates (2)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

6His, N-terminus (3)

GST (1)

GST, N-terminus (1)

His-SUMO (1)

Species

Human (5)

Mouse (1)

Source

E. coli (2)

Wheat Germ Extract (2)

Yeast (2)

Purification

Purified (2)

Select

IHC-plus™ MLKL Antibody (clone 3B2) LS-B6865

(4.0) Rating

Antibody:

MLKL Mouse anti-Human Monoclonal (3B2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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MLKL Antibody (aa107-156) LS-B13161

Antibody:

MLKL Rabbit anti-Human Polyclonal (aa107-156) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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MLKL Antibody (aa107-156, HRP) LS-C457002

Antibody:

MLKL Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody

Reactivity:

Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MLKL Antibody (aa107-156, Biotin) LS-C457000

Antibody:

MLKL Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody

Reactivity:

Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

MLKL Antibody (aa443-472) LS-C164488

Antibody:

MLKL Rabbit anti-Mouse Polyclonal (aa443-472) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

200 µl/$393

Select

MLKL Antibody (aa1-471, Biotin) LS-C371881

Antibody:

MLKL Rabbit anti-Human Polyclonal (aa1-471) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

Human MLKL (Sandwich ELISA) ELISA Kit - LS-F18428

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Mouse MLKL Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G23454

(4.0) Rating

(1) Publication(s)

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

56.3 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

Select

Mouse MLKL (Sandwich ELISA) ELISA Kit - LS-F18429

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human MLKL Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G23445

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

56.48 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

Select

MLKL Antibody (aa110-135) LS-C809661

Antibody:

MLKL Rabbit anti-Human Polyclonal (aa110-135) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

Human MLKL Protein (Recombinant His-SUMO) (Full Length) - LS-G21871

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

70.44 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

MLKL Antibody LS-C748501

Antibody:

MLKL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

MLKL Antibody LS-C668443

Antibody:

MLKL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

MLKL Antibody (40-120 aa, N-terminal) LS-C384570

Antibody:

MLKL Rabbit anti-Human Polyclonal (40-120 aa, N-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MLKL Antibody LS-C309015

Antibody:

MLKL Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

Human MLKL Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G136510

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

58.5 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

Select

MLKL Antibody LS-C833992

Antibody:

MLKL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

MLKL Antibody LS-C748500

Antibody:

MLKL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

MLKL Antibody LS-C748499

Antibody:

MLKL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

MLKL Antibody (aa443-472) LS-C323026

Antibody:

MLKL Rabbit anti-Mouse Polyclonal (aa443-472) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MLKL Antibody (aa443-472, Biotin) LS-C263236

Antibody:

MLKL Rabbit anti-Mouse Polyclonal (aa443-472) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MLKL Antibody (aa443-472, APC) LS-C263233

Antibody:

MLKL Rabbit anti-Mouse Polyclonal (aa443-472) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• APC

• Unconjugated
• Biotin
• APC

Select

MLKL Antibody LS-C830721

Antibody:

MLKL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

MLKL Antibody LS-C833110

Antibody:

MLKL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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