Mitofusin 2 / MFN2

mitofusin 2

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

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Products

ELISA Kits (6)

Type

Custom (2)

Sandwich (4)

Target

Mitofusin 2 / MFN2 (6)

Reactivity

Human (3)

Mouse (1)

Rat (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (5)

Publications

No (6)

Sample Type

Cell Lysates (2)

Plasma (2)

Serum (2)

Tissue Homogenates (3)

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Human Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F31902

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F65541

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat Mitofusin 2 / MFN2 (Custom) ELISA Kit - LS-F65266

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$669

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Rat Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F74255

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Mouse Mitofusin 2 / MFN2 (Custom) ELISA Kit - LS-F65505

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$669

Select

Human Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F25496

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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