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Mineralocorticoid Receptor
nuclear receptor subfamily 3, group C, member 2
The mineralocorticoid receptor (MR), a NR3 Steroid Receptor, has been shown to affect hypothalamic-pituitary-adrenocortical axis activity in the brain, sodium and potassium transport, and stress-related psychiatric diseases such as major depression. MR binds aldosterone and glucocorticoid with equal affinity, and the binding specificity is regulated by the enzyme 11beta-hydroxysteroid-dehydrogenase type II. Mutations in the mineralocorticoid receptor cause autosomal dominant pseudohypoaldosteronism type I and early onset hypertension. Three isoforms of MR have been documented in human: wild type, MR+4, which contains four additional amino acids in the DNA-binding domain due to alternative splicing between exons 3 and 4, and hMR delta5,6, resulting from an alternative-splicing event that skips exons 5 and 6 of the human MR gene.
| Gene Name: | nuclear receptor subfamily 3, group C, member 2 |
| Family/Subfamily: | NHR , NR3 Steroid receptor |
| Synonyms: | NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR |
| Target Sequences: | NM_000901 NP_000892.2 P08235 |
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(39)
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Mineralocorticoid Receptor
(39)
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Publications
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(39)
Mineralocorticoid Receptor Mouse anti-Human Monoclonal (H10E4C9F) Antibody
Chicken, Rabbit, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$565
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa651-700) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa651-700) (HRP) Antibody
Bovine, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa651-700) (Biotin) Antibody
Bovine, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa651-700) (FITC) Antibody
Bovine, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$575
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
Mineralocorticoid Receptor Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$307; 120 µl/$367; 200 µl/$457
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$307; 120 µl/$367; 200 µl/$457
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa966-984) Antibody
Chicken, Rat, Horse, Bat, Mouse, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa654-683) Antibody
Human
WB
Unconjugated
400 µl/$393
Mineralocorticoid Receptor Rabbit anti-Human Polyclonal (aa950-984) Antibody
Mouse, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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