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MGLL / Monoacylglycerol Lipase

monoglyceride lipase

MAG Lipase is a lipase that functions together with hormone-sensitive lipase to hydrolyze intracellular triglyceride stores in adipocytes and other cell types to form fatty acids and glycerol. MAG lipase also works with lipoprotein lipase to hydrolyze monoglycerides resulting from degradation of lipoprotein triglycerides. It is localized in the enteric nervous system to function in the regulation of levels of endocannabinoids, and regulates intestinal motility and has a role in digestion.

Gene Name: monoglyceride lipase
Synonyms: MGLL, HUK5, Lysophospholipase homolog, MGL, Monoacylglycerol lipase, HU-K5, Lysophospholipase-like, MAGL, Monoglyceride lipase
Target Sequences: NM_007283 NP_009214.1 Q99685

Publications (2)

1
Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by ß-Adrenergic Receptors in Brown Adipocytes. Oue K, Zhang J, Harada-Hada K, Asano S, Yamawaki Y, Hayashiuchi M, Furusho H, Takata T, Irifune M, Hirata M, Kanematsu T. The Journal of biological chemistry. 2016 291:4185-96. (WB; Human) [Full Text Article] [PubMed:26706316] [PMC:PMC4759193]
2
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages. Jinlong Yin , Sung Soo Kim , Eunji Choi , Young Taek Oh , Weiwei Lin, Tae-Hoon Kim, Jason K Sa, Jun Hee Hong, Se Hwan Park, Hyung Joon Kwon, Xiong Jin, Yeonhee You, Ji Hye Kim, Hyunggee Kim, Jaekyoung Son, Jeongwu Lee, Do-Hyun Nam, Kui Son Choi, Bingyang Shi, Ho-Shin Gwak, Heon Yoo, Antonio Iavarone, Jong Heon Kim, Jong Bae Park. Nature communications. 2020 June;11:2978. [Full Text Article] [PubMed:32532977] [PMC:PMC7293269] Related Antibodies: LS-C173047.

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
MGLL / Monoacylglycerol Lipase (10)
No (10)
6His, N-terminus (3)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (2)
Purified (6)
MGLL / Monoacylglycerol Lipase Protein - Recombinant Lipase, Monoacylglycerol By SDS-PAGE
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E. coli
6His, N-terminus
40.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
MGLL / Monoacylglycerol Lipase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
MGLL / Monoacylglycerol Lipase Protein - 12.5% SDS-PAGE of human MGLL stained with Coomassie Blue
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Wheat Germ Extract
GST
60.7 kDa
10 µg/$479; 25 µg/$670
MGLL / Monoacylglycerol Lipase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.1 kDa
20 µg/$150
MGLL / Monoacylglycerol Lipase Protein - Purified recombinant protein MGLL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
34.1 kDa
20 µg/$1,107
MGLL / Monoacylglycerol Lipase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.1 kDa
100 µg/$494
MGLL / Monoacylglycerol Lipase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
MGLL / Monoacylglycerol Lipase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MGLL / Monoacylglycerol Lipase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
MGLL / Monoacylglycerol Lipase Protein
Select
E. coli
His
50 µg/$392; 250 µg/$872; 10 µg/$286; 20 µg/$348; 100 µg/$511; 500 µg/$1,355
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).