MFSD2A

major facilitator superfamily domain containing 2A

Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis By similarity. Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

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Products

Antibodies (6)

Proteins (4)

ELISA Kits (2)

Type

Over-Expression Lysate (2)

Primary (6)

Recombinant (2)

Sandwich (2)

Target

MFSD2A (12)

Reactivity

Human (7)

Mouse (2)

Rat (1)

Chimpanzee (3)

Monkey (3)

Orangutan (3)

Rabbit (3)

Application

IHC (2)

IHC-P (1)

WB (6)

ELISA (1)

IF (1)

Host

rabbit (6)

Product Group

IHCPlus (1)

Isotype

IgG (2)

Clonality

polyclonal pc (6)

Format

96-Well Strip Plate (2)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (3)

Epitope

N-Terminus (4)

aa450-543 (1)

Publications

No (11)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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MFSD2A Antibody LS-B5348

(4.0) Rating

(1) Publication(s)

Antibody:

MFSD2A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Human MFSD2A (Sandwich ELISA) ELISA Kit - LS-F17826

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Mouse MFSD2A (Sandwich ELISA) ELISA Kit - LS-F17827

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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MFSD2A Antibody (N-Terminus) LS-C186690

Antibody:

MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MFSD2A Antibody (N-Terminus, HRP) LS-C453354

Antibody:

MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MFSD2A Antibody (N-Terminus, Biotin) LS-C453353

Antibody:

MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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MFSD2A Antibody (N-Terminus, FITC) LS-C453355

Antibody:

MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human MFSD2A Protein (Recombinant GST) (Full Length) - LS-G35846

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

85 kDa

Price:

10 µg/$479; 25 µg/$670

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MFSD2A Antibody (aa450-543) LS-C666753

Antibody:

MFSD2A Rabbit anti-Human Polyclonal (aa450-543) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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Human MFSD2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94167

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.4 kDa

Price:

20 µg/$150

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MFSD2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108525

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.4 kDa

Price:

100 µg/$494

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Human MFSD2A Protein (Recombinant His) (aa453-530) - LS-G140880

Source:

E. coli

Sequence Length:

77 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

8.58 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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