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MFGE8 /Lactadherin

milk fat globule-EGF factor 8 protein

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization By similarity. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Gene Name: milk fat globule-EGF factor 8 protein
Synonyms: MFGE8, Breast epithelial antigen BA46, EDIL1, HP47, Lactadherin, Medin, MFGM, Milk fat globule-EGF factor 8, HsT19888, OAcGD3S, SPAG10, Sperm associated antigen 10, MFG-E8, SED1, Sperm surface protein hP47, BA46, HMFG
Target Sequences: NM_005928 NP_005919.2 Q08431

Publications (2)

1
Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia. Mwila-Kazimbaya K, Garcia MP, Bosomprah S, Laban NM, Chisenga CC, Permar SR, Simuyandi M, Munsaka S, Chilengi R. PloS one. 2017 December;12:e0189351. [Full Text Article] [PubMed:29284036] [PMC:PMC5746212]
2
Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt Pathway. Deng KQ, Li J, She ZG, Gong J, Cheng WL, Gong FH, Zhu XY, Zhang Y, Wang Z, Li H. Hypertension. 2017 October;70:770-779. [Full Text Article] [PubMed:28827473]

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ELISA Kits (20)
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MFGE8 /Lactadherin (20)
Human (9)
Mouse (6)
Rat (2)
Bovine (1)
Monkey (1)
Pig (1)
96-Well Microplate (5)
96-Well Strip Plate (14)
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Yes (2)
Breast Milk (1)
Cell Culture Supernatants (9)
Cell Lysates (3)
Cerebrospinal Fluid (1)
Plasma (15)
Saliva (1)
Serum (16)
Tissue Homogenates (5)
Urine (3)
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine
1 Plate/$699
MFGE8 /Lactadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$798
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
1 - 600 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$549
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich CLIA
Human
31.2 - 2000 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$816
MFGE8 /Lactadherin ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$585
MFGE8 /Lactadherin ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
MFGE8 /Lactadherin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$624
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
781.25 - 50000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cerebrospinal Fluid, Serum, Urine
1 Plate/$968
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).