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METTL1 is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Gene Name: | methyltransferase like 1 |
Synonyms: | METTL1, C12orf1, D1075-like gene product, Methyltransferase like 1, Methyltransferase-like 1, TRM8, TRMT8, TRNA(m7G46)-methyltransferase, YDL201w |
Target Sequences: | Y18642 NP_005362.3 Q9UBP6 |
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