MEF2C

myocyte enhancer factor 2C

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

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ELISA Kits (4)

Type

Cell-Based Phosphorylation (1)

Custom (1)

DNA Binding (1)

DNA Binding Phosphorylation (1)

Target

MEF2C (4)

Reactivity

Human (4)

Mouse (3)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

Publications

No (4)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (2)

Nuclear Lysates (2)

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Mouse/Human Phospho-MEF2C (Ser396) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F912

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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Mouse/Human MEF2C (DNA-Binding ELISA) ELISA Kit - LS-F801

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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Mouse/Human Phospho-MEF2C (Ser396) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1736

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human MEF2C (Custom ELISA) ELISA Kit - LS-F50650

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$823

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