MEF2C

myocyte enhancer factor 2C

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

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Products

Antibodies (129)

Proteins (6)

ELISA Kits (4)

Type

Cell-Based Phosphorylation (1)

Custom (1)

DNA Binding (1)

DNA Binding Phosphorylation (1)

Over-Expression Lysate (4)

Primary (129)

Recombinant (2)

Target

MEF2C (139)

Reactivity

Human (131)

Mouse (37)

Rat (13)

Bat (3)

Bovine (1)

Chicken (1)

Chimpanzee (3)

Dog (3)

Gibbon (6)

Guinea pig (1)

Hamster (3)

Horse (3)

Monkey (6)

Non-Human Primate (1)

Orangutan (3)

Pig (7)

Rabbit (3)

Sheep (1)

Xenopus (3)

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Application

IHC (65)

IHC-P (24)

WB (112)

Flo (14)

DB (27)

ELISA (58)

ICC (2)

IF (17)

IP (1)

Peptide-ELISA (5)

Host

rabbit (103)

mouse (25)

sheep (1)

Product Group

IHCPlus (3)

Isotype

IgG (82)

IgG1 (12)

IgG2a (6)

IgG2b (6)

Clonality

monoclonal mc (24)

polyclonal pc (105)

Clone

6H2G2 (2)

OTI1B6 (2)

OTI1D1 (2)

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OTI2E2 (2)

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12 x 8-Well Microstrips (2)

96-Well Microplate (2)

APC Conjugated (8)

Azide-free (7)

Biotin Conjugated (11)

Carrier-free (11)

FITC Conjugated (11)

HRP Conjugated (11)

PE Conjugated (8)

Unconjugated (80)

Epitope

pSer396 (11)

pSer387 (9)

Ser387 (7)

Ser59 (7)

Thr300 (7)

pThr20 (7)

pThr300 (7)

Internal (4)

aa359-408 (4)

aa78-127 (4)

340-420 aa (2)

aa170-380 (2)

330-410 aa (1)

Amino Acid: 1-125 (1)

C-Terminus (1)

Ile390 (1)

Ser396 (1)

aa135-239 (1)

aa362-411 (1)

aa411-460 (1)

p396 (1)

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Publications

No (137)

Yes (2)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (2)

Nuclear Lysates (2)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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MEF2C Antibody (C-Terminus) LS-C356188

(4.0) Rating

(1) Publication(s)

Antibody:

MEF2C Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Zebrafish, Pig, Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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MEF2C Antibody (aa78-127) LS-C31031

(4.0) Rating

(1) Publication(s)

Antibody:

MEF2C Rabbit anti-Mouse Polyclonal (aa78-127) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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MEF2C Antibody (clone OTI1H5) LS-C337296

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI1H5) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

MEF2C Antibody (clone OTI1H5, Carrier-free) LS-C785758

Antibody:

MEF2C Mouse anti-Human Monoclonal (Carrier-free) (OTI1H5) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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IHC-plus™ MEF2C Antibody (Ser59) LS-B3630

(4.0) Rating

Antibody:

MEF2C Rabbit anti-Human Polyclonal (Ser59) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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MEF2C Antibody (clone 6H2G2) LS-C169151

Antibody:

MEF2C Mouse anti-Human Monoclonal (6H2G2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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MEF2C Antibody (clone OTI4B10) LS-C172621

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI4B10) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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Mouse/Human Phospho-MEF2C (Ser396) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F912

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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MEF2C Antibody (phospho-Ser396) LS-C199247

Antibody:

MEF2C Rabbit anti-Human Polyclonal (pSer396) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MEF2C Antibody (Thr300) LS-C100010

Antibody:

MEF2C Rabbit anti-Human Polyclonal (Thr300) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MEF2C Antibody (Ser387, PE) LS-C279823

Antibody:

MEF2C Rabbit anti-Human Polyclonal (Ser387) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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MEF2C Antibody (phospho-Ser396) LS-C335769

Antibody:

MEF2C Rabbit anti-Human Polyclonal (pSer396) Antibody

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

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MEF2C Antibody (clone OTI2D2) LS-C337280

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI2D2) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

MEF2C Antibody (clone OTI2D2, Carrier-free) LS-C785705

Antibody:

MEF2C Mouse anti-Human Monoclonal (Carrier-free) (OTI2D2) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

MEF2C Antibody (clone OTI1B6) LS-C172866

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI1B6) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

MEF2C Antibody (clone OTI1B6, Carrier-free) LS-C785886

Antibody:

MEF2C Mouse anti-Human Monoclonal (Carrier-free) (OTI1B6) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

MEF2C Antibody (clone OTI4F7) LS-C172812

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI4F7) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

MEF2C Antibody (clone OTI4F7, Carrier-free) LS-C785811

Antibody:

MEF2C Mouse anti-Human Monoclonal (Carrier-free) (OTI4F7) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

MEF2C Antibody (clone OTI4G8) LS-C337294

Antibody:

MEF2C Mouse anti-Human Monoclonal (OTI4G8) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

MEF2C Antibody (clone OTI4G8, Carrier-free) LS-C785749

Antibody:

MEF2C Mouse anti-Human Monoclonal (Carrier-free) (OTI4G8) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

IHC-plus™ MEF2C Antibody (aa362-411) LS-B13320

(4.0) Rating

Antibody:

MEF2C Rabbit anti-Human Polyclonal (aa362-411) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$515

Select

MEF2C Antibody LS-C417209

Antibody:

MEF2C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

MEF2C Antibody (Ser387) LS-C100007

Antibody:

MEF2C Rabbit anti-Human Polyclonal (Ser387) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MEF2C Antibody LS-C666715

Antibody:

MEF2C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

MEF2C Antibody (Amino Acid: 1-125, clone 6H2G2) LS-C759662

Antibody:

MEF2C Mouse anti-Human Monoclonal (Amino Acid: 1-125) (6H2G2) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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