Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
MDK / Midkine
midkine (neurite growth-promoting factor 2)
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.
| Gene Name: | midkine (neurite growth-promoting factor 2) |
| Synonyms: | MDK, ARAP, MK, MK1, NEGF2, Midkine, Retinoic acid inducible factor |
| Target Sequences: | NM_002391 NP_002382.1 P21741 |
Publications (3)
1
High-level soluble expression, purification and characterization of active human midkine from Escherichia coli. Yan WK, Goette M, Hofmann G, Zaror I, Sim J. Protein expression and purification. 2010 70:270-6. (WB)
[PubMed:19883768]
2
DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma. Meng X, Duan C, Pang H, Chen Q, Han B, Zha C, Dinislam M, Wu P, Li Z, Zhao S, Wang R, Lin L, Jiang C, Cai J. EBioMedicine. 2019 March;41:185-199. [Full Text Article]
[PubMed:30773478]
[PMC:PMC6442002]
3
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, Kapoun AM, Garcia KC, Hoey T, Murriel CL, Sage J. Nature. 2017 May;545:360-364. [Full Text Article]
[PubMed:28489825]
[PMC:PMC5776014]
☰ Filters
Products
Antibodies
(85)
Type
Primary
(85)
Target
MDK / Midkine
(85)
Reactivity
Human
(69)
Mouse
(17)
Rat
(15)
Bat
(3)
Chimpanzee
(3)
Dog
(3)
Guinea pig
(3)
Monkey
(3)
Pig
(4)
Application
IHC
(7)
IHC-P
(3)
WB
(82)
ELISA
(18)
IF
(2)
IP
(2)
Peptide-ELISA
(2)
Host
rabbit
(65)
mouse
(20)
Product Group
IHCPlus
(2)
Isotype
IgG
(34)
IgG1
(7)
IgG1,k
(1)
Clonality
monoclonal mc
(19)
polyclonal pc
(66)
Clone
07
(1)
3G1-E1-G10-G8-D9-F3
(2)
C1
(1)
OTI6C8
(2)
OTI8C6
(2)
Format
APC
(5)
APC Conjugated
(6)
Biotin Conjugated
(13)
Carrier-free
(2)
Cy3 Conjugated
(5)
Cy7 Conjugated
(5)
FITC Conjugated
(9)
HRP Conjugated
(8)
PE Conjugated
(6)
Preservative Free
(7)
Unconjugated
(33)
Epitope
aa22-143
(26)
aa22-140
(16)
aa21-143
(5)
C-Terminus
(4)
Internal
(3)
aa113-143
(1)
aa94-143
(1)
Publications
No
(85)
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MDK / Midkine Mouse anti-Human Monoclonal (aa21-143) (OTI6C8) Antibody
Human
WB
Unconjugated
100 µl/$434
MDK / Midkine Rabbit anti-Human Polyclonal (aa113-143) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (3G1-E1-G10-G8-D9-F3) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (Biotin) (3G1-E1-G10-G8-D9-F3) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
MDK / Midkine Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (07) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
MDK / Midkine Mouse anti-Human Monoclonal (aa22-143) (C1) Antibody
Human
WB
Unconjugated
100 µl/$305; 200 µl/$345; 500 µl/$479; 1 ml/$547; 2 ml/$725; 5 ml/$1,192
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$331
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$657
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MDK / Midkine Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MDK / Midkine Rabbit anti-Human Polyclonal (Internal) Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
MDK / Midkine Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
MDK / Midkine Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Pig, Human
IP, WB
Unconjugated
100 µl/$299
MDK / Midkine Rabbit anti-Human Polyclonal (aa94-143) Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25
of 85
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
