MDK / Midkine

midkine (neurite growth-promoting factor 2)

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.

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Products

Antibodies (85)

ELISA Kits (30)

Proteins (23)

Type

Competitive EIA (2)

Custom (1)

Development Kit (3)

Over-Expression Lysate (8)

Primary (85)

Recombinant (15)

Sandwich (22)

Sandwich CLIA (2)

Target

MDK / Midkine (138)

Reactivity

Human (82)

Mouse (24)

Rat (19)

Bat (3)

Chicken (1)

Chimpanzee (3)

Dog (3)

Guinea pig (4)

Monkey (4)

Pig (4)

Porcine (1)

Rabbit (1)

Sheep (1)

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Application

IHC (7)

IHC-P (3)

WB (82)

ELISA (18)

IF (2)

IP (2)

Peptide-ELISA (2)

Host

rabbit (65)

mouse (20)

Product Group

DevKit Core (1)

DevKit DuoPlus (2)

IHCPlus (2)

Isotype

IgG (34)

IgG1 (7)

IgG1,k (1)

Clonality

monoclonal mc (19)

polyclonal pc (66)

Clone

07 (1)

3G1-E1-G10-G8-D9-F3 (2)

C1 (1)

OTI6C8 (2)

OTI8C6 (2)

Format

1000 Wells (1)

12 x 8-Well Microstrips (2)

96-Well Microplate (3)

96-Well Strip Plate (20)

Antibody Pair and Standard (2)

APC (5)

APC Conjugated (6)

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Epitope

aa22-143 (26)

aa22-140 (16)

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C-Terminus (4)

Internal (3)

aa113-143 (1)

aa94-143 (1)

Publications

No (137)

Yes (1)

Sample Type

Cell Culture Supernatants (10)

Cell Lysates (6)

Citrate Plasma (2)

EDTA Plasma (2)

Heparin Plasma (2)

Plasma (18)

Serum (20)

Tissue Homogenates (8)

Tag

6His, N-terminus (1)

GST (2)

His (1)

His, N-Terminal (1)

His-S (2)

His-T7 (1)

Myc-DDK (Flag) (11)

Species

Human (16)

Mouse (2)

Rat (1)

Source

293T Cells (4)

E. coli (11)

HEK 293 Cells (7)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (4)

Select

IHC-plus™ MDK / Midkine Antibody LS-B14850

(4.0) Rating

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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MDK / Midkine Antibody (aa21-143, clone OTI6C8) LS-C340363

Antibody:

MDK / Midkine Mouse anti-Human Monoclonal (aa21-143) (OTI6C8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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MDK / Midkine Antibody (aa113-143) LS-C164107

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal (aa113-143) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MDK / Midkine Antibody (clone 3G1-E1-G10-G8-D9-F3, Preservative Free) LS-C343164

Antibody:

MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (3G1-E1-G10-G8-D9-F3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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Human MDK / Midkine (Sandwich ELISA) ELISA Kit - LS-F589

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$414

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Mouse MDK / Midkine (Sandwich ELISA) ELISA Kit - LS-F5765

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Mouse MDK / Midkine (Sandwich ELISA) ELISA Kit - LS-F12048

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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MDK / Midkine Antibody (aa22-140) LS-C295370

Antibody:

MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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MDK / Midkine Antibody (aa22-140, Biotin) LS-C297533

Antibody:

MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

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MDK / Midkine Antibody (aa22-140, PE) LS-C721956

Antibody:

MDK / Midkine Rabbit anti-Mouse Polyclonal (aa22-140) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269

• Unconjugated
• Biotin
• PE

• Unconjugated
• Biotin
• PE

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MDK / Midkine Antibody (Preservative Free) LS-C343018

Antibody:

MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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IHC-plus™ MDK / Midkine Antibody LS-B8221

(4.0) Rating

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human MDK / Midkine (Sandwich ELISA) ELISA Kit - LS-F3634

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.123 - 30 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$635

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MDK / Midkine Antibody (clone 07, Preservative Free) LS-C820098

Antibody:

MDK / Midkine Mouse anti-Human Monoclonal (Preservative Free) (07) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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MDK / Midkine Antibody (aa22-143, clone C1) LS-C292482

Antibody:

MDK / Midkine Mouse anti-Human Monoclonal (aa22-143) (C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$305; 200 µl/$345; 500 µl/$479; 1 ml/$547; 2 ml/$725; 5 ml/$1,192

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Human MDK / Midkine Protein (Recombinant) - LS-G131414

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~14 kDa

Price:

20 µg/$301; 100 µg/$490; 1 mg/$1,891

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MDK / Midkine Antibody LS-C809501

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Rat MDK / Midkine (Sandwich ELISA) ELISA Kit - LS-F7818

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Human MDK / Midkine (Competitive EIA) ELISA Kit - LS-F27747

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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DevKit Core Human MDK / Midkine ELISA Development Kit - LS-F31233

Type:

Development Kit

Format:

1000 Wells

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 405nm (ABTS)

Price:

1 Test/$540

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MDK / Midkine Antibody LS-C660327

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$331

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MDK / Midkine Antibody LS-C124131

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$657

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MDK / Midkine Antibody LS-C400881

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MDK / Midkine Antibody (Preservative Free) LS-C343522

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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MDK / Midkine Antibody (Internal) LS-C386952

Antibody:

MDK / Midkine Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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