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MCPH1

microcephalin 1

MCPH1 is a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Gene Name: microcephalin 1
Synonyms: MCPH1, BRIT1, MCT, Microcephalin, Microcephalin 1
Target Sequences: NM_024596 NP_078872.2 Q8NEM0

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
MCPH1 (4)
No (4)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
MCPH1 Protein - 12.5% SDS-PAGE of human MCPH1 stained with Coomassie Blue
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Wheat Germ Extract
GST
94.2 kDa
10 µg/$479; 25 µg/$670
MCPH1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MCPH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.6 kDa
20 µg/$215
MCPH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.6 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).