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MC3R / MC3 Receptor is a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Gene Name: | melanocortin 3 receptor |
Family/Subfamily: | GPCR , Melanocortin |
Synonyms: | MC3R, BMIQ9, MC3 receptor, Melanocortin receptor 3, OB20, MC3, MC3-R, Melanocortin 3 receptor, OQTL |
Target Sequences: | NM_019888 NP_063941.3 P41968 |
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