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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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MC2R / ACTHR / ACTH Receptor
melanocortin 2 receptor (adrenocorticotropic hormone)
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
| Gene Name: | melanocortin 2 receptor (adrenocorticotropic hormone) |
| Family/Subfamily: | GPCR , Melanocortin |
| Synonyms: | MC2R, ACTHR, ACTH receptor, ACTH-R, Adrenocorticotropic receptor, Adrenocorticotropin receptor, Melanocortin 2 receptor, Melanocortin receptor 2, MC2-R, MC2 receptor |
| Target Sequences: | NM_000529 NP_000520.1 Q01718 |
Publications (2)
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