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Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Gene Name: | membrane bound O-acyltransferase domain containing 2 |
Synonyms: | MBOAT2, LPAAT, LPEAT, Lyso-PA acyltransferase, Lyso-PE acyltransferase, OACT2, LPLAT 2 |
Target Sequences: | NM_138799 NP_620154.2 Q6ZWT7 |
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