MASTL / GW

microtubule associated serine/threonine kinase-like

Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

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Products

Antibodies (46)

Proteins (4)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (2)

Primary (46)

Recombinant (2)

Target

MASTL / GW (51)

Reactivity

Human (40)

Mouse (14)

Rat (4)

Bovine (4)

Chicken (1)

Dog (1)

Gibbon (3)

Horse (3)

Rabbit (3)

Application

IHC (6)

IHC-P (5)

WB (35)

Flo (1)

ELISA (29)

ICC (5)

IF (8)

IP (1)

Peptide-ELISA (2)

Host

rabbit (33)

mouse (13)

Isotype

IgG (26)

IgG1,k (13)

Clonality

monoclonal mc (13)

polyclonal pc (33)

Clone

235CT7.8.2.3 (6)

4B4-1B11 (1)

Format

96-Well Microplate (1)

APC Conjugated (4)

Azide-free (3)

Biotin Conjugated (6)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (20)

Epitope

aa561-589 (7)

aa505-554 (4)

aa550-600 (2)

790-870 aa, C-terminal (1)

C-Terminus (1)

C-terminal (1)

aa821-870 (1)

Publications

No (51)

Sample Type

Adherent Cell Cultures (1)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

MASTL / GW Antibody (aa505-554) LS-C135854

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (aa505-554) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MASTL / GW Antibody (aa550-600) LS-C288944

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (aa550-600) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

MASTL / GW Antibody LS-C164044

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MASTL / GW Antibody LS-C673318

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

MASTL / GW Antibody (clone 235CT7.8.2.3) LS-C319175

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MASTL / GW Antibody (clone 235CT7.8.2.3, Biotin) LS-C212497

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (Biotin) (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (clone 235CT7.8.2.3, FITC) LS-C212498

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (FITC) (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (clone 235CT7.8.2.3, APC) LS-C212496

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (APC) (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (clone 235CT7.8.2.3, Azide-free, HRP) LS-C212499

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (Azide-free) (HRP) (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MASTL / GW Antibody (clone 235CT7.8.2.3, PE) LS-C212500

Antibody:

MASTL / GW Mouse anti-Human Monoclonal (PE) (235CT7.8.2.3) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MASTL / GW Antibody LS-C809299

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MASTL / GW Antibody (790-870 aa, C-terminal) LS-C386407

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (790-870 aa, C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MASTL / GW Antibody LS-C164043

Antibody:

MASTL / GW Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MASTL / GW Antibody (C-Terminus) LS-C356177

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

Select

MASTL / GW Antibody (aa561-589) LS-C322873

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MASTL / GW Antibody (aa561-589, Biotin) LS-C215744

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (aa561-589, FITC) LS-C215745

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (aa561-589, APC) LS-C215743

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MASTL / GW Antibody (aa561-589, Azide-free, HRP) LS-C215746

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MASTL / GW Antibody (aa561-589, PE) LS-C215747

Antibody:

MASTL / GW Rabbit anti-Mouse Polyclonal (aa561-589) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MASTL / GW Antibody LS-C327840

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MASTL / GW Antibody (C-terminal) LS-C384447

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MASTL / GW Antibody LS-C823146

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MASTL / GW Antibody LS-C824917

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MASTL / GW Antibody (aa821-870) LS-C119208

Antibody:

MASTL / GW Rabbit anti-Human Polyclonal (aa821-870) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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