MASP1 / MASP

mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

MASP1 / MASP is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.

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Products

Proteins (15)

Type

Over-Expression Lysate (6)

Recombinant (9)

Target

MASP1 / MASP (15)

Publications

No (15)

Tag

6His, C-terminus (2)

6His, N-terminus (1)

GST (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (8)

Species

Human (11)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human MASP1 / MASP Protein (Recombinant 6His, C-terminus) (His20-Arg728) - LS-G39113

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.68kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Mouse MASP1 / MASP Protein (Recombinant His-T7) (aa25-453) - LS-G24542

Source:

E. coli

Tag:

His-T7

Molecular Weight:

52.6 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human MASP1 / MASP Protein (Recombinant 6His, N-terminus) (aa20-699) - LS-G23019

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

79.03 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human MASP1 / MASP Protein (Recombinant His-T7) (aa20-447) - LS-G24541

Source:

E. coli

Tag:

His-T7

Molecular Weight:

52.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human MASP1 / MASP Protein (Recombinant GST) (Full Length) - LS-G29951

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MASP1 / MASP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65300

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49 kDa

Price:

20 µg/$1,107

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Human MASP1 / MASP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65301

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.6 kDa

Price:

20 µg/$1,107

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MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99587

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.25 kDa

Price:

100 µg/$710

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Human MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75299

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.25 kDa

Price:

20 µg/$215

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Human MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75298

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

20 µg/$150

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Human MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75300

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.6 kDa

Price:

20 µg/$215

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MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107134

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.6 kDa

Price:

100 µg/$710

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MASP1 / MASP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120754

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

100 µg/$494

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Human MASP1 / MASP Protein (Recombinant 6His, C-terminus) (His20-Arg728) - LS-G140276

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.7 kDa

Price:

10 µg/$344; 50 µg/$584

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Human MASP1 / MASP Protein (Recombinant His-SUMO) (aa20-699) - LS-G20955

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

93.03 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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