MASP1 / MASP

mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

MASP1 / MASP is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.

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Products

Antibodies (55)

Proteins (15)

ELISA Kits (14)

Type

Custom (2)

Over-Expression Lysate (6)

Primary (55)

Recombinant (9)

Sandwich (11)

Sandwich CLIA (1)

Target

MASP1 / MASP (84)

Reactivity

Human (62)

Mouse (25)

Rat (16)

Chicken (1)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Monkey (4)

Orangutan (3)

Porcine (1)

Rabbit (4)

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Application

IHC (2)

IHC-P (2)

WB (55)

ELISA (13)

ICC (1)

IP (5)

Peptide-ELISA (1)

Host

rabbit (49)

mouse (5)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (22)

IgG1 (3)

IgG2a (2)

Clonality

monoclonal mc (5)

polyclonal pc (50)

Clone

1E2 (1)

2B11 (1)

2D5B6 (1)

38:12-3 (1)

4H2A9 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (10)

APC (2)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (4)

Unconjugated (22)

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Epitope

aa20-447 (8)

aa25-453 (8)

aa481-507 (7)

Internal (6)

aa110-159 (4)

370-450 aa, Internal (1)

aa399-448 (1)

heavy chain, Cleaved-Arg448 (1)

Publications

No (84)

Sample Type

Cell Culture Supernatants (1)

Plasma (9)

Serum (9)

Tissue Homogenates (2)

Tag

6His, C-terminus (2)

6His, N-terminus (1)

GST (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (8)

Species

Human (11)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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MASP1 / MASP Antibody (aa25-453) LS-C372833

Antibody:

MASP1 / MASP Rabbit anti-Mouse Polyclonal (aa25-453) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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IHC-plus™ MASP1 / MASP Antibody LS-B15153

(4.0) Rating

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Mouse MASP1 / MASP (Sandwich ELISA) ELISA Kit - LS-F5806

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Human MASP1 / MASP Protein (Recombinant 6His, C-terminus) (His20-Arg728) - LS-G39113

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.68kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human MASP1 / MASP (Sandwich ELISA) ELISA Kit - LS-F49893

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.614 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Mouse MASP1 / MASP Protein (Recombinant His-T7) (aa25-453) - LS-G24542

Source:

E. coli

Tag:

His-T7

Molecular Weight:

52.6 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human MASP1 / MASP Protein (Recombinant 6His, N-terminus) (aa20-699) - LS-G23019

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

79.03 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human MASP1 / MASP (Sandwich ELISA) ELISA Kit - LS-F32848

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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MASP1 / MASP Antibody (aa110-159) LS-C151567

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MASP1 / MASP Antibody (aa110-159, HRP) LS-C471482

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa110-159) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

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MASP1 / MASP Antibody (Internal) LS-C354421

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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Human MASP1 / MASP (Sandwich ELISA) ELISA Kit - LS-F5691

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

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MASP1 / MASP Antibody (aa399-448) LS-C121073

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa399-448) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MASP1 / MASP Antibody (aa481-507) LS-C158103

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa481-507) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human MASP1 / MASP Protein (Recombinant His-T7) (aa20-447) - LS-G24541

Source:

E. coli

Tag:

His-T7

Molecular Weight:

52.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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MASP1 / MASP Antibody LS-C408866

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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MASP1 / MASP Antibody (clone 2D5B6) LS-C757294

Antibody:

MASP1 / MASP Mouse anti-Human Monoclonal (2D5B6) Antibody

Reactivity:

Human

Applications:

IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$652

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MASP1 / MASP Antibody LS-C666658

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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MASP1 / MASP Antibody (aa481-507) LS-C322865

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa481-507) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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MASP1 / MASP Antibody (aa481-507, Biotin) LS-C207222

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (aa481-507) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

MASP1 / MASP Antibody (clone 2B11) LS-C210271

Antibody:

MASP1 / MASP Mouse anti-Human Monoclonal (2B11) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$723

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MASP1 / MASP Antibody (clone 1E2) LS-C210270

Antibody:

MASP1 / MASP Mouse anti-Human Monoclonal (1E2) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$723

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MASP1 / MASP Antibody (370-450 aa, Internal) LS-C380536

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (370-450 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MASP1 / MASP Antibody (clone 4H2A9) LS-C757295

Antibody:

MASP1 / MASP Mouse anti-Human Monoclonal (4H2A9) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$652

Select

MASP1 / MASP Antibody (heavy chain, Cleaved-Arg448) LS-C826708

Antibody:

MASP1 / MASP Rabbit anti-Human Polyclonal (heavy chain, Cleaved-Arg448) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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