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MAS1 / MAS

MAS1 oncogene

Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Gene Name: MAS1 oncogene
Family/Subfamily: GPCR , Orphan-A
Synonyms: MAS1, Mas proto-oncogene, Proto-oncogene Mas, MAS, MAS1 oncogene
Target Sequences: NM_002377 NP_002368.1 P04201

Publications (3)

1
Changes in the renin angiotensin system during the development of colorectal cancer liver metastases. Neo JH, Ager EI, Angus PW, Zhu J, Herath CB, Christophi C. BMC cancer. 2010 10:134. (IHC-P; Mouse) [Full Text Article] [PubMed:20380732] [PMC:PMC2860361] Related Antibodies: LS-A1528.
2
Expression and function of the ACE2/angiotensin(1-7)/Mas axis in osteosarcoma cell lines U-2 OS and MNNG-HOS. Ender SA, Dallmer A, Lässig F, Lendeckel U, Wolke C. Molecular medicine reports. 2014 August;10:804-10. (Human) [Full Text Article] [PubMed:24858078] Related Antibodies: LS-B3564.
3
Mitochondrial assembly receptor expression is an independent prognosticator for patients with oral tongue squamous cell carcinoma. Su YY, Chen CH, Chien CY, Lin WC, Huang WT, Li SH. Journal of the renin-angiotensin-aldosterone system : JRAAS. 2017 July;18:1470320317717904. (Human) [Full Text Article] [PubMed:28747140] [PMC:PMC5843911] Related Antibodies: LS-A1528.

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Products
ELISA Kits (5)
Sandwich (5)
MAS1 / MAS (5)
Human (1)
Mouse (2)
Rat (2)
96-Well Strip Plate (5)
No (5)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
MAS1 / MAS ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
MAS1 / MAS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
MAS1 / MAS ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.078 - 5 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
MAS1 / MAS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
MAS1 / MAS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).