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MARK1 / MARK
MAP/microtubule affinity-regulating kinase 1
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
| Gene Name: | MAP/microtubule affinity-regulating kinase 1 |
| Family/Subfamily: | Protein Kinase , MARK |
| Synonyms: | MARK1, KIAA1477, Par1c, PAR1 homolog c, MARK, Par-1c |
| Target Sequences: | NM_018650 NP_061120.3 Q9P0L2 |
Publications (1)
1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. Molecular and cellular biology. 2008 28:2414-25.
[PubMed:18227155]
[PMC:PMC2268441]
Related Antibodies: LS-C98353.
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(41)
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(41)
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MARK1 / MARK
(41)
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(41)
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(27)
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(3)
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(2)
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(1)
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(1)
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(23)
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(7)
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(37)
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(29)
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rabbit
(41)
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(3)
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(33)
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polyclonal pc
(41)
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(4)
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(4)
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(4)
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(4)
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(4)
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(4)
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(21)
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aa6-40
(7)
aa600-627
(7)
aa643-674
(7)
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(7)
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(2)
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(40)
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(1)
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Fast Shipping
MARK1 / MARK Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
MARK1 / MARK Rabbit anti-Human Polyclonal (aa671-700) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Fast Shipping
MARK1 / MARK Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
MARK1 / MARK Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386
MARK1 / MARK Rabbit anti-Mouse Polyclonal (aa600-627) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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