MAPT / Tau

microtubule-associated protein tau

Tau promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU.

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Products

Proteins (37)

Type

Over-Expression Lysate (11)

Recombinant (26)

Target

MAPT / Tau (37)

Application

SDS-PAGE (1)

Publications

No (37)

Tag

6His, C-terminus (2)

6His, N-terminus (2)

GST, N-terminus (1)

His (8)

His,N-terminus (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (14)

Species

Human (26)

Mouse (2)

Rat (3)

Rhesus monkey (1)

Source

293T Cells (6)

E. coli (20)

HEK 293 Cells (8)

Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (8)

Low Endotoxin Level

Low endotoxin level (6)

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Human MAPT / Tau Protein (Recombinant) (Met1-Leu441) - LS-G39800

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.85kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Rhesus monkey MAPT / Tau Protein (Recombinant His-SUMO) (Full Length) - LS-G20953

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

63.8 kD

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Mouse MAPT / Tau Protein (Recombinant 6His, N-terminus) (aa2-733) - LS-G57218

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Human MAPT / Tau Protein (Recombinant His) - LS-G892

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Rat MAPT / Tau Protein (Recombinant His) (Full Length) - LS-G20954

Source:

E. coli

Tag:

His

Molecular Weight:

82.5 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human MAPT / Tau Protein (Recombinant 6His, C-terminus) (Gln249-Gln381) - LS-G38709

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.37kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human MAPT / Tau Protein (Recombinant His) - LS-G1292

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739; 20 µg/$486; 100 µg/$1,177; 250 µg/$1,788; 500 µg/$3,043

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Human MAPT / Tau Protein (Recombinant His) - LS-G1073

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human MAPT / Tau Protein (Recombinant His,N-terminus) (Ala2-Leu352) - LS-G47668

Source:

E. coli

Tag:

His,N-terminus

Application:

SDS-PAGE

Molecular Weight:

The recombinant human MAPT consists of 367 amino acids and predicts a molecular mass of 38.7 kDa. It migrates as an approximately 40-50 kDa band in SDS-PAGE under reducing conditions.

Price:

50 µg/$441

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77368

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.8 kDa

Price:

20 µg/$150

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Human MAPT / Tau Protein (Recombinant GST, N-terminus) (aa167-266) - LS-G59180

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MAPT / Tau Protein (Recombinant His) (Ala2-Leu352) - LS-G97684

Source:

E. coli

Tag:

His

Molecular Weight:

38.7 kDa

Price:

50 µg/$721

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77369

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.7 kDa

Price:

20 µg/$215

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77370

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.8 kDa

Price:

20 µg/$150

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77371

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.7 kDa

Price:

20 µg/$215

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77372

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.7 kDa

Price:

20 µg/$215

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Human MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77373

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$150

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Human MAPT / Tau Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66290

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.7 kDa

Price:

20 µg/$1,107

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Human MAPT / Tau Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66291

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.8 kDa

Price:

20 µg/$1,107

Select

Human MAPT / Tau Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66292

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

20 µg/$1,107

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MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124465

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.8 kDa

Price:

100 µg/$494

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MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112492

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.8 kDa

Price:

100 µg/$494

Select

MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112493

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.7 kDa

Price:

100 µg/$710

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MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112496

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.6 kDa

Price:

100 µg/$494

Select

MAPT / Tau Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100674

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.7 kDa

Price:

100 µg/$710

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