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ERK8 is a MAPK type protein kinase that is activated by a Src-dependent signaling pathway. The protein contains two SH3-binding motifs in its C-terminal region and has been shown to associate with the c-Src SH3 domain in vitro and co-immunoprecipitate with c-Src in vivo.
Gene Name: | mitogen-activated protein kinase 15 |
Family/Subfamily: | Protein Kinase , MAPK |
Synonyms: | MAPK15, ERK7, ERK-8, MAPK 15, MAP kinase 15, ERK-7, ERK8 |
Target Sequences: | NM_139021 NP_620590.2 Q8TD08 |
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