MAP4K4

mitogen-activated protein kinase kinase kinase kinase 4

MAP4K4 is a MSN protein kinase. The protein has a structure similar to other GCK (Group I) kinases and contains two consensus SH3 binding motifs, which have been shown to interact with the SH3 domains of the SH2/SH3 adapter protein Nck. NIK can be activated by tumor necrosis factor (TNF)-alpha. Activated NIK has been shown to activate c-Jun N-terminal kinase (JNK) and to bind and activate the plasma membrane Na-H exchanger NHE1. In NIK(-/-) mice, mesodermal and endodermal cells of the primitive streak fail to migrate to their correct location, and embryos die between embryonic day (E) 9.5 and E10.5. At least three protein isoforms have been reported.

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Products

Antibodies (36)

Proteins (2)

Type

Over-Expression Lysate (2)

Primary (36)

Target

MAP4K4 (38)

Reactivity

Human (36)

Mouse (17)

Rat (3)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (1)

Pig (3)

Rabbit (3)

Xenopus (3)

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Application

IHC (8)

IHC-P (5)

WB (29)

DB (6)

ELISA (19)

ICC (1)

IF (6)

IP (2)

Peptide-ELISA (2)

Host

rabbit (30)

mouse (6)

Product Group

IHCPlus (2)

Isotype

IgG (22)

IgG1 (5)

IgG1,k (1)

Clonality

monoclonal mc (7)

polyclonal pc (29)

Clone

3C7B5 (2)

4A5 (1)

4H9E7 (2)

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APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (23)

Epitope

aa506-534 (7)

pSer629 (6)

aa287-336 (4)

Amino Acid: 400-500 (2)

aa550-600 (2)

380-460 aa, Internal (1)

Ala553 (1)

Arg430 (1)

aa406-455 (1)

aa850-900 (1)

aa931-947 (1)

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Publications

No (38)

Tag

Myc-DDK (Flag) (2)

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Human (1)

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293T Cells (1)

HEK 293 Cells (1)

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MAP4K4 Antibody (aa287-336) LS-B5815

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa287-336) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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MAP4K4 Antibody (aa287-336, HRP) LS-C451969

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rat, Rabbit, Mouse, Dog, Guinea pig, Bat, Pig, Horse, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MAP4K4 Antibody (aa287-336, Biotin) LS-C451968

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rat, Rabbit, Mouse, Dog, Guinea pig, Bat, Pig, Horse, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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MAP4K4 Antibody (aa287-336, FITC) LS-C451970

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rat, Rabbit, Mouse, Dog, Guinea pig, Bat, Pig, Horse, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ MAP4K4 Antibody (aa931-947) LS-B712

(4.0) Rating

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa931-947) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$545

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MAP4K4 Antibody (aa406-455) LS-C118740

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa406-455) Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MAP4K4 Antibody (380-460 aa, Internal) LS-C383923

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (380-460 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MAP4K4 Antibody (clone 4A5) LS-C105080

Antibody:

MAP4K4 Mouse anti-Human Monoclonal (4A5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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MAP4K4 Antibody (Ala553) LS-C191011

Antibody:

MAP4K4 Rabbit anti-Human Monoclonal (Ala553) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

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MAP4K4 Antibody LS-C416145

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$305; 100 µl/$357

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MAP4K4 Antibody LS-C666634

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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MAP4K4 Antibody LS-C822530

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

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MAP4K4 Antibody (aa550-600) LS-C288299

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (aa550-600) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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MAP4K4 Antibody LS-C800554

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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MAP4K4 Antibody (Arg430) LS-C176891

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (Arg430) Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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MAP4K4 Antibody (aa506-534) LS-C322839

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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MAP4K4 Antibody (aa506-534, Biotin) LS-C215717

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MAP4K4 Antibody (aa506-534, FITC) LS-C215716

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MAP4K4 Antibody (aa506-534, APC) LS-C215715

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MAP4K4 Antibody (aa506-534, Azide-free, HRP) LS-C215718

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MAP4K4 Antibody (aa506-534, PE) LS-C215719

Antibody:

MAP4K4 Rabbit anti-Mouse Polyclonal (aa506-534) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MAP4K4 Antibody (clone 4H9E7) LS-C108875

Antibody:

MAP4K4 Mouse anti-Human Monoclonal (4H9E7) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$435

Select

MAP4K4 Antibody (clone 3C7B5) LS-C108876

Antibody:

MAP4K4 Mouse anti-Human Monoclonal (3C7B5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$467

Select

MAP4K4 Antibody LS-C812480

Antibody:

MAP4K4 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

MAP4K4 Antibody (phospho-Ser629) LS-C327918

Antibody:

MAP4K4 Rabbit anti-Human Polyclonal (pSer629) Antibody

Reactivity:

Human

Applications:

DB, ELISA

Format:

Unconjugated

Price:

200 µl/$734

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