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MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
| Gene Name: | mucosa associated lymphoid tissue lymphoma translocation gene 1 |
| Family/Subfamily: | Protease , Cysteine C14 |
| Synonyms: | MALT1, Caspase-like protein, MLT, MLT1, Paracaspase, MALT associated translocation |
| Target Sequences: | NM_006785 NP_006776.1 Q9UDY8 |
Publications (1)
1
Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applications. Chng WJ, Remstein ED, Fonseca R, Bergsagel PL, Vrana JA, Kurtin PJ, Dogan A. Blood. 2009 113:635-45. (WB)
[PubMed:18974375]
[PMC:PMC2628370]
☰ Filters
Products
Proteins
(10)
Type
Over-Expression Lysate
(4)
Recombinant
(6)
Target
MALT1
(10)
Publications
No
(10)
Tag
GST, N-terminus
(2)
Myc-DDK (Flag)
(6)
Myc-DDK (Flag), C-terminus
(1)
TRX-6His, N-terminus
(1)
Species
Human
(7)
Mouse
(1)
Source
293T Cells
(2)
E. coli
(1)
HEK 293 Cells
(5)
Wheat Germ Extract
(2)
Purification
Purified
(2)
Wheat Germ Extract
GST, N-terminus
117.5 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
90.9 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
90.9 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag), C-terminus
92.5 kDa
20 µg/$1,224
HEK 293 Cells
Myc-DDK (Flag)
90.9 kDa
100 µg/$494
E. coli
TRX-6His, N-terminus
27 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949
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