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Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Gene Name: | mucosa associated lymphoid tissue lymphoma translocation gene 1 |
Family/Subfamily: | Protease , Cysteine C14 |
Synonyms: | MALT1, Caspase-like protein, MLT, MLT1, Paracaspase, MALT associated translocation |
Target Sequences: | NM_006785 NP_006776.1 Q9UDY8 |
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