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MAGEA6

melanoma antigen family A, 6

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

Gene Name: melanoma antigen family A, 6
Synonyms: MAGEA6, CT1.6, MAGE-3b, MAGE3B antigen, Melanoma-associated antigen 6, MAGE3B, Cancer/testis antigen 1.6, MAGE-6 antigen, MAGE6, Melanoma antigen family A, 6
Target Sequences: NM_005363 NP_005354.1 P43360

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
MAGEA6 (6)
No (6)
GST (1)
His (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
MAGEA6 Protein - 12.5% SDS-PAGE of human MAGEA6 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.3 kDa
10 µg/$479; 25 µg/$670
MAGEA6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.7 kDa
20 µg/$150
MAGEA6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.7 kDa
20 µg/$150
MAGEA6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.7 kDa
100 µg/$494
MAGEA6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.7 kDa
100 µg/$494
MAGEA6 Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).