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MAFK

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K

The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.

Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
Synonyms: MAFK, NFE2U, p18, Transcription factor MafK
Target Sequences: NM_002360 NP_002351.1 O60675

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Products
Proteins (8)
Recombinant (8)
MAFK (8)
No (8)
10His, N-terminus + Myc, C-terminus (4)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST, N-terminus (1)
His (1)
Human (3)
Mouse (5)
Baculovirus (2)
E. coli (3)
Mammalian Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (7)
MAFK Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Baculovirus
10His, N-terminus + Myc, C-terminus
100 µg/$810; 20 µg/$387; 1 mg/$1,678
MAFK Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Baculovirus
10His, N-terminus + Myc, C-terminus
100 µg/$810; 20 µg/$387; 1 mg/$1,678
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
10His, N-terminus + Myc, C-terminus
21.5 kDa
100 µg/$1,009; 20 µg/$431; 1 mg/$3,451
MAFK Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
19.5 kDa
100 µg/$570; 20 µg/$395; 1 mg/$1,973
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).