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Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response.
Gene Name: | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
Synonyms: | MAFF, HMafF, Transcription factor MafF, U-MAF |
Target Sequences: | NM_012323 NP_036455.1 Q9ULX9 |
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