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LYVE1

lymphatic vessel endothelial hyaluronan receptor 1

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Gene Name: lymphatic vessel endothelial hyaluronan receptor 1
Synonyms: LYVE1, CRSBP-1, CRSBP1, Hyaluronic acid receptor, LYVE-1, XLKD1, HAR
Target Sequences: NM_006691 NP_006682.2

Publications (1)

1
Trafficking of a dual-modality magnetic resonance and fluorescence imaging superparamagnetic iron oxide-based nanoprobe to lymph nodes. Bumb A, Regino CA, Egen JG, Bernardo M, Dobson PJ, Germain RN, Choyke PL, Brechbiel MW. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2011 13:1163-72. (ICC, IHC-Fr; Mouse) [PubMed:21080233] [PMC:PMC3116972]

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
LYVE1 (7)
No (7)
6His, C-terminus (2)
Fc (1)
GST (1)
Mouse IgG2a Fc, N-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (2)
293T Cells (1)
HEK 293 Cells (2)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (4)
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.6kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
LYVE1 Protein - 12.5% SDS-PAGE of human XLKD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.16 kDa
10 µg/$479; 25 µg/$670
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Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
49.1 kDa
50 µg/$721
LYVE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35 kDa
20 µg/$150
LYVE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35 kDa
100 µg/$494
Select
HEK 293 Cells
Mouse IgG2a Fc, N-terminus
Less than 5.0 EU/mg protein (determined by LAL method).
~70 kDa (SDS-PAGE)
50 µg/$442
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.6 kDa
10 µg/$297; 50 µg/$460
Viewing 1-7 of 7 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).