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LTBP2

latent transforming growth factor beta binding protein 2

LTBP2 belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion.

Gene Name: latent transforming growth factor beta binding protein 2
Synonyms: LTBP2, C14orf141, GLC3D, LTBP-2, MSTP031, WMS3, MSPKA
Target Sequences: NM_000428 NP_000419.1 Q14767

Publications (1)

1
An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis10<sup> Children's Medical Research Institute, University of Sydney, Sydney, NSW 2006, Australia; Military Institute of Hygiene and Epidemiology, Biological Threats Identification and Countermeasure Centre, Pulawy 24-100, Poland12<sup> Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC 3800, Australia14<sup> Sackler School of Biomedica. Ben Roediger, Quintin Lee, Shweta Tikoo, Joanna C A Cobbin, James M Henderson, Mika Jormakka, Matthew B O'Rourke, Matthew P Padula, Natalia Pinello, Marisa Henry, Maria Wynne, Sara F Santagostino, Cory F Brayton, Lorna Rasmussen, Leszek Lisowski, Szun S Tay, David C Harris, John F Bertram, John P Dowling, Patrick Bertolino, Jack H Lai, Wengen Wu, William W Bachovchin, Justin J-L Wong, Mark D Gorrell, Babak Shaban, Edward C Holmes, Christopher J Jolly, Sébastien Monette, Wolfgang Weninger. Cell. 2018 Oct;175:530-543.e24. [Full Text Article] [PubMed:30220458] [PMC:PMC6800251]

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LTBP2 Protein
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E. coli
His, N-Terminal
35.3 kDa
50 µg/$452; 10 µg/$283; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
LTBP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).