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LTB4R2 / BLT2
leukotriene B4 receptor 2
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
| Gene Name: | leukotriene B4 receptor 2 |
| Family/Subfamily: | GPCR , Chemoattractant |
| Synonyms: | LTB4R2, BLT2, BLTR2, Blt-2, BLT2R, JULF2, LTB4-R2, Hblt2, KPG_004, Leukotriene B4 receptor 2, Leukotriene B4 receptor BLT2, LTB4 receptor JULF2, LTB4-R 2 |
| Target Sequences: | NM_019839 NP_062813.2 Q9NPC1 |
Publications (3)
1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Bck M, Bu DX, Brnstrm R, Sheikine Y, Yan ZQ, Hansson GK. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:17501-6. (IHC-Fr; Human)
[PubMed:16293697]
[PMC:PMC1297663]
Related Antibodies: LS-A2099.
2
Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2. Seo JM, Park S, Kim JH. The Journal of biological chemistry. 2012 Apr;287:13840-9. [Full Text Article]
[PubMed:22396544]
[PMC:PMC3340142]
Related Antibodies: LS-A2099.
3
BLT2 promotes the invasion and metastasis of aggressive bladder cancer cells through a reactive oxygen species-linked pathway. Kim EY, Seo JM, Kim C, Lee JE, Lee KM, Kim JH. Free radical biology & medicine. 2010 Sep;49:1072-81. [Full Text Article]
[PubMed:20600831]
Related Antibodies: LS-A2097.
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Antibodies
(22)
Type
Primary
(22)
Target
LTB4R2 / BLT2
(22)
Reactivity
Human
(22)
Mouse
(2)
Rat
(2)
Bat
(3)
Bovine
(3)
Chimpanzee
(3)
Monkey
(4)
Application
IHC
(3)
IHC-Fr
(1)
IHC-P
(3)
WB
(19)
Flo
(1)
ELISA
(7)
Host
rabbit
(22)
Product Group
GPCR Database Antibodies
(3)
IHCPlus
(1)
PathPlus Cancer
(2)
Isotype
IgG
(9)
Clonality
polyclonal pc
(22)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(3)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(1)
Unconjugated
(11)
Epitope
aa333-361
(7)
C-Terminus
(5)
aa283-332
(4)
Cytoplasmic Domain
(1)
N-Terminus
(1)
Publications
No
(20)
Yes
(2)
Cancer
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human, Monkey
Flo, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$440
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Cancer
Fast Shipping
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$289
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
1 Each/$431
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa283-332) Antibody
Human
WB
Unconjugated
100 µl/$424
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa283-332) (HRP) Antibody
Bovine, Bat, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa283-332) (Biotin) Antibody
Bovine, Bat, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa283-332) (FITC) Antibody
Bovine, Bat, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (aa333-361) Antibody
Human
WB
Unconjugated
400 µl/$393
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
LTB4R2 / BLT2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
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product results
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