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LTA / TNF Beta

lymphotoxin alpha

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Gene Name: lymphotoxin alpha
Family/Subfamily: TNF , not assigned-TNF
Synonyms: LTA, Lymphotoxin-alpha, LT-alpha, TNFSF1, TNF-beta, TNFB, Tumor necrosis factor beta, LT, TNF Beta
Target Sequences: NM_000595 NP_000586.2 P01374

☰ Filters
Products
Proteins (30)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (6)
Recombinant (22)
LTA / TNF Beta (30)
No (30)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (2)
GST (2)
GST, N-terminus (1)
His (3)
His, N-Terminal (2)
His-T7 (4)
Myc-DDK (Flag) (6)
Dog (1)
Human (21)
Mouse (2)
Pig (2)
Rabbit (1)
Rat (1)
293T Cells (2)
E. coli (18)
HEK 293 Cells (7)
Wheat Germ Extract (3)
Purified (8)
Low endotoxin level (7)
Biologically active (6)
LTA / TNF Beta Protein - Recombinant Tumor Necrosis Factor Beta By SDS-PAGE
Select
E. coli
His
18.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.6 kDa
5 µg/$268; 20 µg/$349
LTA / TNF Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus + Myc, C-terminus
23.6 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
LTA / TNF Beta Protein
Select
E. coli
None
Biologically active
18.7 kDa
10 µg/$282; 100 µg/$957; 500 µg/$1,747
LTA / TNF Beta Protein - 12.5% SDS-PAGE of human LTA stained with Coomassie Blue
Select
Wheat Germ Extract
GST
48.29 kDa
10 µg/$479; 25 µg/$670
LTA / TNF Beta Protein - 12.5% SDS-PAGE of human LTA stained with Coomassie Blue
Select
Wheat Germ Extract
GST
48.7 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
18.8kD
10 µg/$297; 50 µg/$468; 500 µg/$1,353; 1 mg/$1,725
LTA / TNF Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.35 kDa
20 µg/$150
LTA / TNF Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.35 kDa
20 µg/$150
LTA / TNF Beta Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
HEK 293 Cells
His, N-Terminal
~19 kDa
100 µg/$298
LTA / TNF Beta Protein - Purified recombinant protein LTA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18.6 kDa
20 µg/$1,107
LTA / TNF Beta Protein - Purified recombinant protein LTA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
18.6 kDa
20 µg/$1,107
LTA / TNF Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.35 kDa
100 µg/$494
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
18.8 kDa
20 µg/$360; 100 µg/$728
LTA / TNF Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.35 kDa
100 µg/$494
LTA / TNF Beta Protein - The ED(50) was measured in a cytotoxicity assay using mouse L929 cells in the presence of the metabolic inhibitor actinomycin, and was determined to be less than 0.1 ng/mL.
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~19 kDa
20 µg/$291; 100 µg/$537; 1 mg/$1,891
LTA / TNF Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
18.8 kDa
50 µg/$556; 10 µg/$324; 1 mg/$2,269; 500 µg/$1,639
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
5 µg/$306; 20 µg/$359
Select
E. coli
None
Less than 0.1 ng/µg protein.
18.6 kDa
5 µg/$329; 20 µg/$412; 1000 µg/$3,417
LTA / TNF Beta Protein - Active Tumor Necrosis Factor Beta (TNFb) by WB
Select
E. coli
His, N-Terminal
23kDa
10 µg/$331; 50 µg/$752; 200 µg/$1,367; 100 µg/$1,158; 1 mg/$2,650; 500 µg/$2,147; 5 mg/$5,265; 2 mg/$2,841
Select
HEK 293 Cells
6His, N-terminus
21 kDa
100 µg/$298
Select
HEK 293 Cells
6His, N-terminus
21 kDa
200 µl/$283
Select
E. coli
None
Biologically active
18.6 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$273; 1 mg/$1,740
LTA / TNF Beta Protein - Recombinant Tumor Necrosis Factor Beta By SDS-PAGE
Select
E. coli
His-T7
17.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Viewing 1-25 of 30 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).