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B001/B101
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LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
Synonyms: | LSS, Lanosterol synthase, HOSC, OSC |
Target Sequences: | NM_002340 NP_002331.3 P48449 |
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