LRP6

low density lipoprotein receptor-related protein 6

Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) is a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. LRP6 functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade LRP6 plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. LRP6 undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

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Antibodies (30)

ELISA Kits (14)

Proteins (4)

Type

Competitive EIA (1)

Custom (1)

Over-Expression Lysate (2)

Primary (30)

Recombinant (2)

Sandwich (11)

Sandwich CLIA (1)

Target

LRP6 (48)

Reactivity

Human (36)

Mouse (9)

Rat (6)

Chicken (1)

Dog (1)

Hamster (1)

Horse (1)

Monkey (2)

Pig (1)

Porcine (1)

Rabbit (2)

Sheep (1)

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IHC (14)

IHC-P (5)

WB (24)

Flo (1)

ELISA (10)

IF (2)

IP (1)

Peptide-ELISA (3)

Host

rabbit (28)

mouse (1)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (17)

IgG1 (1)

Clonality

monoclonal mc (2)

polyclonal pc (28)

Clone

1A3F5 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (12)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Preservative Free (1)

Unconjugated (18)

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Epitope

aa981-1213 (8)

aa1531-1560 (7)

pSer1490 (2)

aa1547-1560 (1)

aa20-150 (1)

Publications

No (47)

Yes (1)

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Plasma (7)

Serum (7)

Tissue Homogenates (3)

Tag

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

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IHC-plus™ LRP6 Antibody (aa1547-1560) LS-B5

(4.0) Rating

Antibody:

LRP6 Goat anti-Human Polyclonal (aa1547-1560) Antibody

Reactivity:

Rabbit, Dog, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$375

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LRP6 Antibody (aa1531-1560) LS-C100405

(4.0) Rating

(1) Publication(s)

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human LRP6 Protein (Recombinant His, N-Terminal) (aa981-1213) - LS-G15171

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.4 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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LRP6 Antibody LS-C750044

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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LRP6 Antibody LS-C130478

Antibody:

LRP6 Rabbit anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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Human LRP6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68601

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

178.4 kDa

Price:

20 µg/$1,107

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LRP6 Antibody (clone 1A3F5) LS-C828290

Antibody:

LRP6 Mouse anti-Human Monoclonal (1A3F5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$459

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LRP6 Antibody LS-C748380

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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LRP6 Antibody LS-C804440

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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LRP6 Antibody (Preservative Free) LS-C815638

Antibody:

LRP6 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$302

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LRP6 Antibody (aa20-150) LS-C376041

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa20-150) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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LRP6 Antibody (aa1531-1560) LS-C330510

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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LRP6 Antibody (aa1531-1560, Biotin) LS-C278960

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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LRP6 Antibody (aa1531-1560, FITC) LS-C278961

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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LRP6 Antibody (aa1531-1560, APC) LS-C278959

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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LRP6 Antibody (aa1531-1560, Azide-free, HRP) LS-C278962

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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LRP6 Antibody (aa1531-1560, PE) LS-C278964

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa1531-1560) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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LRP6 Antibody LS-C833088

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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LRP6 Antibody LS-C668317

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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LRP6 Antibody LS-C767933

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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LRP6 Antibody LS-C778663

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$357

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LRP6 Antibody (phospho-Ser1490) LS-C804437

Antibody:

LRP6 Rabbit anti-Human Polyclonal (pSer1490) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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LRP6 Antibody LS-C833425

Antibody:

LRP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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LRP6 Antibody (phospho-Ser1490) LS-C191466

Antibody:

LRP6 Rabbit anti-Human Polyclonal (pSer1490) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$754

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LRP6 Antibody (aa981-1213) LS-C295195

Antibody:

LRP6 Rabbit anti-Human Polyclonal (aa981-1213) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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