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LRIT3 is a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F.
Gene Name: | leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 |
Synonyms: | LRIT3, FIGLER4 |
Target Sequences: | Q3SXY7 Q3SXY7 |
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