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LRCH2 encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants.
Gene Name: | Leucine-rich Repeats And Calponin Homology (CH) Domain Containing 2 |
Synonyms: | LRCH2, DA204F4.4, KIAA1495 |
Target Sequences: | AB040928 BAA96019.1 Q5VUJ6 |
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