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Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
Gene Name: | lipin 2 |
Synonyms: | LPIN2, Lipin 2, KIAA0249, Lipin-2 |
Target Sequences: | NM_014646 NP_055461.1 Q92539 |
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