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20700 44th Avenue W
Lynnwood, WA 98036
Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors.
Gene Name: | lysophosphatidylcholine acyltransferase 4 |
Synonyms: | LPCAT4, 1-AGPAT 7, Acyltransferase like 3, Acyltransferase-like 3, 1-AGP acyltransferase 7, AGPAT7, LPEAT2, PLSC domain containing protein, AYTL3, LPAAT-eta |
Target Sequences: | NM_153613 NP_705841.2 Q643R3 |
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