Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
LPA / Lipoprotein a is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.
Gene Name: | lipoprotein, Lp(a) |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | LPA, AK38, Apo(a), Antiangiogenic AK38 protein, Apolipoprotein(a), Apolipoprotein (a), Lipoprotein a, Lipoprotein (a), Lp(a), APOA, Lipoprotein, Lp(a) |
Target Sequences: | NM_005577 NP_005568.2 P08519 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.