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Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Gene Name: | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
Family/Subfamily: | Phospholipase , not assigned-Phospholipase |
Synonyms: | PLA2G7, GVIIA-PLA2, PAF acetylhydrolase, PAFAD, PAF 2-acylhydrolase, PAFAH, LDL-PLA(2), LP-PLA2, Group-VIIA phospholipase A2, LDL-PLA2 |
Target Sequences: | NM_005084 NP_005075.3 Q13093 |
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