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LNX1 / LNX
ligand of numb-protein X 1, E3 ubiquitin protein ligase
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.
| Gene Name: | ligand of numb-protein X 1, E3 ubiquitin protein ligase |
| Synonyms: | LNX1, Ligand of numb-protein X, LNX, Ligand of Numb-protein X 1, Numb-binding protein 1, PDZRN2 |
| Target Sequences: | NM_032622 NP_116011.2 Q8TBB1 |
Publications (1)
1
Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth10<sup> Center for Experimental Medicine, The First Affiliated Hospital of Nanchang University, 330006, Nanchang, Jiangxi, China. shiwenluo@ncu.edu.cn. Zhengwei Yan #, Minzhang Cheng #, Guohui Hu #, Yao Wang , Shaopeng Zeng, Aidi Huang, Linlin Xu, Yuan Liu, Chao Shi, Libin Deng, Quqin Lu, Hai Rao, Hua Lu , Ye-Guang Chen, Shiwen Luo. Cell death & disease. 2021 Feb;12:199. [Full Text Article]
[PubMed:33608498]
[PMC:PMC7896051]
☰ Filters
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Antibodies
(21)
Type
Primary
(21)
Target
LNX1 / LNX
(21)
Reactivity
Human
(21)
Mouse
(4)
Rat
(3)
Bat
(3)
Bovine
(3)
Chimpanzee
(3)
Dog
(3)
Gibbon
(3)
Horse
(3)
Monkey
(3)
Orangutan
(3)
Pig
(3)
Rabbit
(3)
Application
IHC
(3)
IHC-P
(3)
WB
(15)
ELISA
(11)
IF
(2)
Host
rabbit
(12)
mouse
(9)
Product Group
IHCPlus
(2)
Isotype
IgG
(13)
IgG1
(2)
IgG2a,k
(6)
Clonality
monoclonal mc
(8)
polyclonal pc
(13)
Clone
1H9
(2)
Format
APC Conjugated
(1)
Biotin Conjugated
(3)
Carrier-free
(1)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(1)
Unconjugated
(10)
Epitope
aa431-480
(4)
aa19-119
(1)
aa260-528
(1)
Publications
No
(21)
LNX1 / LNX Mouse anti-Human Monoclonal (1H9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LNX1 / LNX Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-P
Unconjugated
50 µl/$460
LNX1 / LNX Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
LNX1 / LNX Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
LNX1 / LNX Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
LNX1 / LNX Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
LNX1 / LNX Mouse anti-Human Monoclonal (aa19-119) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
LNX1 / LNX Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
LNX1 / LNX Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
LNX1 / LNX Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
LNX1 / LNX Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
LNX1 / LNX Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
LNX1 / LNX Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
LNX1 / LNX Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
LNX1 / LNX Mouse anti-Human Monoclonal (aa260-528) (Carrier-free) (1H9) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
LNX1 / LNX Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
LNX1 / LNX Rabbit anti-Human Polyclonal (aa431-480) Antibody
Human
WB
Unconjugated
100 µl/$397
LNX1 / LNX Rabbit anti-Human Polyclonal (aa431-480) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$442
LNX1 / LNX Rabbit anti-Human Polyclonal (aa431-480) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
LNX1 / LNX Rabbit anti-Human Polyclonal (aa431-480) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$442
LNX1 / LNX Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
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of 21
product results
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