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LMO2

LIM domain only 2 (rhombotin-like 1)

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: LIM domain only 2 (rhombotin-like 1)
Synonyms: LMO2, LIM domain only protein 2, LMO-2, RHOM2, RBTNL1, Rhombotin 2, Rhombotin-like 1, Cysteine-rich protein TTG-2, RBTN2, Rhombotin-2, T-cell translocation gene 2, T-cell translocation protein 2, TTG2
Target Sequences: NM_005574 NP_005565.2 P25791

Publications (1)

1
The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Natkunam Y, Zhao S, Mason DY, Chen J, Taidi B, Jones M, Hammer AS, Hamilton Dutoit S, Lossos IS, Levy R. Blood. 2007 109:1636-42. [PubMed:17038524] [PMC:PMC1794056]

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Proteins (13)
Over-Expression Lysate (8)
Recombinant (5)
LMO2 (13)
No (13)
GST (1)
Myc-DDK (Flag) (12)
Human (9)
293T Cells (4)
HEK 293 Cells (8)
Wheat Germ Extract (1)
Purified (1)
LMO2 Protein - 12.5% SDS-PAGE of human LMO2 stained with Coomassie Blue
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Wheat Germ Extract
GST
43.12 kDa
10 µg/$479; 25 µg/$670
LMO2 Protein - Purified recombinant protein LMO2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$1,107
LMO2 Protein - Purified recombinant protein LMO2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$1,107
LMO2 Protein - Purified recombinant protein LMO2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$1,107
LMO2 Protein - Purified recombinant protein LMO2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$1,107
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$150
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$150
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.2 kDa
20 µg/$150
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$150
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
100 µg/$494
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
100 µg/$494
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
100 µg/$494
LMO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.2 kDa
100 µg/$494
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).