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LL37 / Cathelicidin

cathelicidin antimicrobial peptide

LL37 / Cathelicidin is a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation.

Gene Name: cathelicidin antimicrobial peptide
Synonyms: CAMP, Antibacterial protein fall-39, CAP-18, CRAMP, FALL-39, FALL39, HCAP-18, HSD26, LL37, CAP18
Target Sequences: NM_004345 NP_004336.3 P49913

Publications (2)

1
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection. Kathryn A Patras, Alison Coady, Priyanka Babu, Samuel R Shing, Albert D Ha, Emma Rooholfada, Stephanie L Brandt, Matthew Geriak, Richard L Gallo, Victor Nizet. mSphere. 2020 Apr;5:e00932-19. [Full Text Article] [PubMed:32321824] [PMC:PMC7178553]
2
GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier. Tarutani M, Nakajima K, Uchida Y, Takaishi M, Goto-Inoue N, Ikawa M, Setou M, Kinoshita T, Elias PM, Sano S, Maeda Y. The Journal of investigative dermatology. 2012 Aug;132:2019-25. [Full Text Article] [PubMed:22572823] Related Antibodies: LS-C94098.

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Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
LL37 / Cathelicidin (11)
No (11)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His-SUMO, N-terminus (2)
GST (1)
His (1)
His, N-Terminal (1)
His-GST (1)
His-GST, N-terminus (1)
Myc-DDK (Flag) (3)
Cow (1)
Human (6)
Mouse (1)
Pig (1)
Rat (1)
293T Cells (1)
E. coli (7)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (6)
LL37 / Cathelicidin Protein - Recombinant Cathelicidin Antimicrobial Peptide By SDS-PAGE
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E. coli
His-GST, N-terminus
43.1 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
LL37 / Cathelicidin Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
LL37 / Cathelicidin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
19.1 kDa
20 µg/$150
LL37 / Cathelicidin Protein - 12.5% SDS-PAGE of human CAMP stained with Coomassie Blue
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Wheat Germ Extract
GST
45.7 kDa
2 µg/$439
LL37 / Cathelicidin Protein - Recombinant Cathelicidin Antimicrobial Peptide By SDS-PAGE
Select
E. coli
His, N-Terminal
21.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
LL37 / Cathelicidin Protein - Purified recombinant protein CAMP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
19.1 kDa
20 µg/$1,107
LL37 / Cathelicidin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
19.1 kDa
100 µg/$494
LL37 / Cathelicidin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
LL37 / Cathelicidin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
LL37 / Cathelicidin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
LL37 / Cathelicidin Protein - Recombinant Cathelicidin Antimicrobial Peptide By SDS-PAGE
Select
E. coli
His-GST
43.6 kDa
10 µg/$288; 50 µg/$482; 100 µg/$772; 200 µg/$965; 1 mg/$2,098; 500 µg/$1,627; 5 mg/$3,375; 2 mg/$2,288
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).