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LL37 / Cathelicidin is a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation.
Gene Name: | cathelicidin antimicrobial peptide |
Synonyms: | CAMP, Antibacterial protein fall-39, CAP-18, CRAMP, FALL-39, FALL39, HCAP-18, HSD26, LL37, CAP18 |
Target Sequences: | NM_004345 NP_004336.3 P49913 |
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