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Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1.
Gene Name: | LIM homeobox 3 |
Synonyms: | LHX3, M2-LHX3, LIM/homeobox protein Lhx3, LIM3, LIM homeobox 3, CPHD3, LIM homeobox protein 3, LIM/homeodomain protein LHX3 |
Target Sequences: | NM_014564 NP_055379.1 Q9UBR4 |
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