LGR6

leucine-rich repeat containing G protein-coupled receptor 6

Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

LGR6 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human LGR6 Protein (Recombinant GST) (Full Length) - LS-G34861

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

115.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human LGR6 Protein (Recombinant GST, N-terminus) (aa403-496) - LS-G63034

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88803

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.1 kDa

Price:

20 µg/$215

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Human LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88805

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.1 kDa

Price:

20 µg/$215

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LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127166

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.1 kDa

Price:

100 µg/$710

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LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121314

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.1 kDa

Price:

100 µg/$710

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