LGMN / Legumain

legumain

LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.

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Products

ELISA Kits (12)

Type

Custom (4)

Sandwich (8)

Target

LGMN / Legumain (12)

Reactivity

Human (6)

Mouse (3)

Rat (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (10)

Publications

No (12)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (8)

Serum (9)

Tissue Homogenates (4)

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Human LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F11947

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F8653

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$748

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Mouse LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F16407

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human LGMN / Legumain (Custom ELISA) ELISA Kit - LS-F56831

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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Rat LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F57217

Type:

Sandwich

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Sample Types:

Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

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Human LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F6730

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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Human LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F34757

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F39771

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$699

Select

Mouse LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F39772

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$699

Select

Human LGMN / Legumain (Custom ELISA) ELISA Kit - LS-F357

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$559

Select

Rat LGMN / Legumain (Custom ELISA) ELISA Kit - LS-F16406

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Bovine LGMN / Legumain (Custom ELISA) ELISA Kit - LS-F16408

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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