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LETMD1 / HCCR1

LETM1 domain containing 1

Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.

Gene Name: LETM1 domain containing 1
Synonyms: LETMD1, HCCR-1, HCRR-2, HCCR1, HCCR-2, LETM1 domain containing 1, Regulator of TP53
Target Sequences: NM_015416 NP_056231.3 Q6P1Q0

Publications (2)

1
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2015 35:655-66. (WB; Human) [Full Text Article] [PubMed:25586139] [PMC:PMC4420885]
2
Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1. Kyung-Mi Choi, Jung Hak Kim, Xiangmudong Kong, Meltem Isik, Jin Zhang, Hee-Woong Lim, John C Yoon. Cell reports. 2021 December;37:110104. [Full Text Article] [PubMed:34910916] Related Antibodies: LS-C335200.

☰ Filters
Products
Antibodies (20)
Primary (20)
LETMD1 / HCCR1 (20)
Human (20)
Mouse (8)
Rat (5)
Bovine (8)
Chimpanzee (3)
Dog (3)
Guinea pig (3)
Horse (3)
Rabbit (3)
IHC (10)
IHC-P (6)
WB (17)
ELISA (1)
ICC (1)
IF (3)
Peptide-ELISA (1)
rabbit (19)
mouse (1)
Product Group
IHCPlus (1)
IgG (6)
polyclonal pc (20)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa162-347 (8)
aa271-320 (4)
No (19)
Yes (1)
LETMD1 / HCCR1 Antibody - Immunohistochemistry of paraffin-embedded human kidney cancer using LETMD1 antibody at dilution of 1:200 (x400 lens).
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389; 200 µl/$503
LETMD1 / HCCR1 Antibody - Immunohistochemical analysis of HCCR-1 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
LETMD1 / HCCR1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa271-320) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
LETMD1 / HCCR1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa271-320) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
LETMD1 / HCCR1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa271-320) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
LETMD1 / HCCR1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa271-320) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
LETMD1 / HCCR1 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LETMD1 / HCCR1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using LETMD1 Polyclonal Antibody at dilution of 1:30.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
LETMD1 / HCCR1 Antibody - Western blot of extracts of PANC1 cell lines, using LETMD1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) Antibody
Bovine, Human
WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (HRP) Antibody
Bovine, Human
WB
HRP Conjugated
100 µl/$351; 200 µl/$410; 500 µl/$615; 1 ml/$769; 2 ml/$1,006; 5 ml/$1,748
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (Biotin) Antibody
Bovine, Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (FITC) Antibody
Bovine, Human
WB
FITC Conjugated
100 µl/$361; 200 µl/$426; 500 µl/$663; 1 ml/$822; 2 ml/$1,063; 5 ml/$1,883
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (APC) Antibody
Bovine, Human
WB
APC Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (PE) Antibody
Bovine, Human
WB
PE Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (APC, Cy7) Antibody
Bovine, Human
WB
APC, Cy7 Conjugated
100 µl/$533; 200 µl/$709; 500 µl/$1,229; 1 ml/$1,537; 2 ml/$2,151; 5 ml/$4,033
LETMD1 / HCCR1 Antibody - Western blot of LETMD1 / HCCR1 antibody.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal (aa162-347) (Cy3) Antibody
Bovine, Human
WB
Cy3 Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689
LETMD1 / HCCR1 Antibody - Immunochemical staining of human LETMD1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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LETMD1 / HCCR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
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LETMD1 / HCCR1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).