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LEPR / Leptin Receptor

leptin receptor

LEPR / Leptin Receptor belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Gene Name: leptin receptor
Synonyms: LEPR, CD295 antigen, HuB219, LEP-R, OB receptor, LEPRD, OB-R, OBR, CD295, DB, Leptin receptor
Target Sequences: NM_002303 NP_002294.2 P48357

Publications (1)

1
High Fat Diet-induced Breast Cancer Model in Rat. Wu MJ, Chang CJ. Bio-protocol. 2016 July;6:pii: e1852. (Human) [Full Text Article] [PubMed:28573159] [PMC:PMC5448410] Related Antibodies: LS-C261832.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (4)
Recombinant (14)
LEPR / Leptin Receptor (18)
No (18)
10His, C-terminus (1)
Fc, C-terminus (2)
Fc-His, C-terminus (1)
GST, N-terminus (1)
His (1)
His, C-Terminal (1)
His, N-Terminal (1)
His,C-terminus (1)
His-S (1)
His-T7 (2)
Mouse IgG Fc, C-terminus (1)
Myc-DDK (Flag) (4)
Human (11)
Mouse (4)
Rat (1)
293F Cells (1)
293T Cells (2)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (3)
Human (5)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (8)
LEPR / Leptin Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
94.9kD
10 µg/$262; 50 µg/$321; 500 µg/$802; 1 mg/$1,113
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
95 kDa
100 µg/$793; 1 mg/$4,191
LEPR / Leptin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
132.55 kDa
100 µg/$710
LEPR / Leptin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
109.39 kDa
20 µg/$215
LEPR / Leptin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
132.55 kDa
20 µg/$215
LEPR / Leptin Receptor Protein - Recombinant Human LEPR (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
120.4 kDa
10 µg/$266; 50 µg/$377
LEPR / Leptin Receptor Protein - Recombinant Mouse Leptin Receptor/LEPR/CD295 (C-mFc)
Select
Human
Mouse IgG Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
118.5 kDa
10 µg/$327; 50 µg/$574
LEPR / Leptin Receptor Protein - Recombinant Mouse Leptin Receptor/LEPR/CD295 (C-10His)
Select
Human
10His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
93 kDa
10 µg/$327; 50 µg/$574
LEPR / Leptin Receptor Protein - Recombinant Mouse Leptin Receptor/LEPR/CD295 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
119.1 kDa
10 µg/$294; 50 µg/$460
LEPR / Leptin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
109.39 kDa
100 µg/$710
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
94.9 kDa
10 µg/$262; 50 µg/$317
LEPR / Leptin Receptor Protein - Eukaryotic Leptin Receptor (LEPR) by SDS-PAGE
Select
293F Cells
His, N-Terminal
95kDa
10 µg/$319; 50 µg/$682; 200 µg/$1,270; 100 µg/$1,071; 1 mg/$2,526; 500 µg/$2,025; 5 mg/$4,761; 2 mg/$2,718
Select
CHO Cells
None
93.5 kDa or 130-150 kDa
100 µg/$349; 20 µg/$268
LEPR / Leptin Receptor Protein - Recombinant  Leptin Receptor By SDS-PAGE
Select
E. coli
His-S
23.7 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
LEPR / Leptin Receptor Protein - Recombinant  Leptin Receptor By SDS-PAGE
Select
E. coli
His-T7
19.3 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Select
HEK 293 Cells
Fc-His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
121.4 kDa
100 µg/$793; 1 mg/$4,191
LEPR / Leptin Receptor Protein - Recombinant Leptin Receptor By SDS-PAGE
Select
E. coli
His-T7
30.2 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Viewing 1-18 of 18 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).