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LEPR / Leptin Receptor

leptin receptor

LEPR / Leptin Receptor belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Gene Name: leptin receptor
Synonyms: LEPR, CD295 antigen, HuB219, LEP-R, OB receptor, LEPRD, OB-R, OBR, CD295, DB, Leptin receptor
Target Sequences: NM_002303 NP_002294.2 P48357

Publications (1)

1
High Fat Diet-induced Breast Cancer Model in Rat. Wu MJ, Chang CJ. Bio-protocol. 2016 July;6:pii: e1852. (Human) [Full Text Article] [PubMed:28573159] [PMC:PMC5448410] Related Antibodies: LS-C261832.

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Antibodies (73)
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LEPR / Leptin Receptor (120)
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LEPR / Leptin Receptor Antibody - Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
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LEPR / Leptin Receptor Goat anti-Human Polyclonal (aa829-841) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
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LEPR / Leptin Receptor Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$657
LEPR / Leptin Receptor Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer tissue.
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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LEPR / Leptin Receptor Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
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LEPR / Leptin Receptor Chicken anti-Rat Polyclonal Antibody
Rat
IF, IHC
Unconjugated
100 µl/$550
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LEPR / Leptin Receptor Rabbit anti-Rat Polyclonal (aa577-594) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µl/$924
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LEPR / Leptin Receptor Rabbit anti-Mouse Polyclonal (aa25-208) Antibody
Mouse
WB
Unconjugated
100 µg/$449
LEPR / Leptin Receptor ELISA Kit
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Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
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LEPR / Leptin Receptor Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$826
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LEPR / Leptin Receptor Mouse anti-Human Monoclonal (2F1) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$554
LEPR / Leptin Receptor Antibody - IHC of Ob-R (L662) pAb in paraffin-embedded human brain tissue.
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (Leu662) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (aa957-986) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (aa957-986) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (aa957-986) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
LEPR / Leptin Receptor Antibody - Western blot of LEPR / Leptin Receptor antibody.
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LEPR / Leptin Receptor Rabbit anti-Rat Polyclonal (aa238-375) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
LEPR / Leptin Receptor Antibody - Western blot of LEPR / Leptin Receptor antibody.
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LEPR / Leptin Receptor Rabbit anti-Mouse Polyclonal (aa22-203) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
LEPR / Leptin Receptor Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LEPR / Leptin Receptor Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using LEPR Polyclonal Antibody at dilution of 1:30(×200)
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
LEPR / Leptin Receptor Antibody - Immunohistochemistry analysis of Ob-R antibody in paraffin-embedded human brain tissue.
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (aa613-662) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
10 µg/$318; 100 µg/$470
Select
LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
LEPR / Leptin Receptor Antibody - Immunofluorescent analysis of HepG2 cells using LEPR Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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LEPR / Leptin Receptor Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 120 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).