LEF1

lymphoid enhancer-binding factor 1

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin promoter in a CTNNB1-independent manner, and is involved in reducing cellular aggregation and increasing cell migration of pancreatic cancer cells. Isoform 1 transcriptionally activates MYC and CCND1 expression and enhances proliferation of pancreatic tumor cells.

☰ Filters

Products

Antibodies (47)

Proteins (8)

ELISA Kits (3)

Type

Over-Expression Lysate (6)

Primary (47)

Recombinant (2)

Sandwich (3)

Target

LEF1 (58)

Reactivity

Human (48)

Mouse (20)

Rat (15)

Bat (3)

Bovine (6)

Chicken (3)

Chimpanzee (9)

Dog (6)

Gibbon (9)

Goat (3)

Guinea pig (9)

Horse (6)

Monkey (9)

Pig (6)

Rabbit (3)

Xenopus (3)

Zebrafish (3)

more less

Application

IHC (16)

IHC-Fr (2)

IHC-P (11)

WB (42)

Flo (1)

ELISA (23)

ICC (2)

IF (6)

IP (4)

Peptide-ELISA (2)

Host

rabbit (34)

mouse (13)

Product Group

IHCPlus (1)

Isotype

IgG (29)

IgG1 (4)

IgG1,k (7)

IgG2b (2)

Clonality

monoclonal mc (16)

polyclonal pc (31)

Clone

1866CT561.78.3 (1)

1A4B11 (1)

3G5F9 (1)

EP310 (2)

OTI10A7 (2)

Format

96-Well Strip Plate (3)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (6)

Carrier-free (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (2)

Ready-to-Use (1)

Unconjugated (25)

Epitope

aa10-37 (8)

aa282-331 (4)

aa51-100 (4)

aa72-121 (4)

pSer42 (2)

20-100 aa (1)

Internal (1)

Pro82 (1)

aa1-85 (1)

aa250-300 (1)

aa349-399 (1)

more less

Publications

No (58)

Sample Type

Plasma (3)

Serum (3)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (6)

Species

Human (5)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

LEF1 Antibody (aa282-331) LS-C30951

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa282-331) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

Select

LEF1 Antibody (aa282-331, HRP) LS-C427839

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa282-331) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

LEF1 Antibody (aa282-331, Biotin) LS-C427837

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa282-331) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

LEF1 Antibody (aa282-331, FITC) LS-C427838

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa282-331) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

LEF1 Antibody (aa51-100) LS-B984

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa51-100) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$375

Select

LEF1 Antibody (aa51-100, HRP) LS-C427841

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa51-100) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

LEF1 Antibody (aa51-100, Biotin) LS-C427840

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa51-100) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

LEF1 Antibody (aa51-100, FITC) LS-C427842

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa51-100) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

LEF1 Antibody (Pro82) LS-C37241

Antibody:

LEF1 Rabbit anti-Human Monoclonal (Pro82) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, ICC, IF, IP, WB

Format:

Unconjugated

Price:

100 µl/$688

Select

LEF1 Antibody (clone OTI10A7) LS-C796486

Antibody:

LEF1 Mouse anti-Human Monoclonal (OTI10A7) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

LEF1 Antibody (clone OTI10A7, Carrier-free) LS-C793159

Antibody:

LEF1 Mouse anti-Human Monoclonal (Carrier-free) (OTI10A7) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

LEF1 Antibody LS-C499233

Antibody:

LEF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

LEF1 Antibody (aa10-37, FITC) LS-C237094

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa10-37) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

LEF1 Antibody (clone EP310) LS-C743628

Antibody:

LEF1 Rabbit anti-Human Monoclonal (EP310) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$447; 0.5 ml/$740; 1 ml/$1,060

Select

LEF1 Antibody (clone EP310, Ready-to-Use) LS-C743516

Antibody:

LEF1 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP310) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

3 ml/$477; 7 ml/$645; 15 ml/$1,105

• Unconjugated
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Ready-to-Use

Select

LEF1 Antibody LS-C809696

Antibody:

LEF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

Select

LEF1 Antibody LS-C754118

Antibody:

LEF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

LEF1 Antibody (aa349-399) LS-C290163

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa349-399) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

LEF1 Antibody (clone 1A4B11) LS-C669393

Antibody:

LEF1 Mouse anti-Human Monoclonal (1A4B11) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

LEF1 Antibody (clone 3G5F9) LS-C669394

Antibody:

LEF1 Mouse anti-Human Monoclonal (3G5F9) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

LEF1 Antibody (aa1-85) LS-C25281

Antibody:

LEF1 Mouse anti-Human Monoclonal (aa1-85) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µg/$845

Select

LEF1 Antibody LS-C308748

Antibody:

LEF1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

LEF1 Antibody (aa10-37) LS-C165738

Antibody:

LEF1 Rabbit anti-Human Polyclonal (aa10-37) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

LEF1 Antibody (clone 1866CT561.78.3) LS-C757822

Antibody:

LEF1 Mouse anti-Human Monoclonal (1866CT561.78.3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

LEF1 Antibody (Internal) LS-C136998

Antibody:

LEF1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$332

Viewing 1-25 of 58 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.